benzyl 4-bromotetrahydro-1(2H)-pyridinecarboxylate - Names and Identifiers
benzyl 4-bromotetrahydro-1(2H)-pyridinecarboxylate - Physico-chemical Properties
Molecular Formula | C13H16BrNO2
|
Molar Mass | 298.18 |
Density | 1.374g/mLat 25°C(lit.) |
Boling Point | 144 °C |
Flash Point | >230°F |
Vapor Presure | 3.91E-06mmHg at 25°C |
pKa | -2.82±0.40(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
Refractive Index | n20/D 1.5590(lit.) |
benzyl 4-bromotetrahydro-1(2H)-pyridinecarboxylate - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 - Wear suitable gloves and eye/face protection
|
WGK Germany | 3 |
HS Code | 29333999 |
Hazard Note | Irritant |
benzyl 4-bromotetrahydro-1(2H)-pyridinecarboxylate - Introduction
benzyl 4-bromotetrahydro-1(2H)-pyridinecarboxylate is an organic compound with the chemical formula C15H15BrN2O and a molecular weight of 324.2g/mol. It is a white or off-white crystalline solid with a high melting point and low solubility with water.
benzyl 4-bromotetrahydro-1(2H)-pyridinecarboxylate is widely used in organic synthesis. It can be used as an important intermediate for the synthesis of other organic compounds, such as drugs, pesticides and dyes. It can participate in electrophilic substitution reaction, nucleophilic substitution reaction, reduction reaction and carbonylation reaction, and has high chemical reaction activity.
The method for preparing benzyl 4-bromotetrahydro-1(2H)-pyridinecarboxylate is usually through a bromination reaction. The specific operation is to react 4-piperidone with bromine in an appropriate solvent, and then add P-toluenesulfonic acid (TosOH) as a catalyst to obtain benzyl 4-bromotetrahydro-1(2H)-pyridinecarboxylate.
When using benzyl 4-bromotetrahydro-1(2H)-pyridinecarboxylate, pay attention to its safety. It may cause irritation to the eyes, skin and respiratory system, so it is necessary to wear appropriate protective measures, such as wearing protective glasses, protective gloves and respirators. In addition, it should be operated in a well-ventilated place to avoid inhaling its vapor or dust. During storage, keep it in a dry, cool place to avoid contact with oxygen, fire and combustibles. When disposing of waste, it should be properly disposed of in accordance with local regulations.
Last Update:2024-04-09 20:52:54